| 2025-01-31 | Oregon Health & Science University | $8.00M | UNDER THIS OPTION WE WILL CONDUCT STUDIES IN RM TO VALIDATE THE EFFICACY OF THE RHCMV/TB VECTOR ORTHOLOG OF THE HUMAN CMV VACCINE CANDIDATE (VIR-1778) CURRENTLY SCHEDULED FOR TESTING IN A PHASE 1 CLINICAL TRIAL. WE… |
| 2023-12-31 | Oregon Health & Science University | $7.49M | RATIONALE: OPTION 4 WAS ORIGINALLY DEVISED AS A PLACEHOLDER EXPERIMENT TO PROVIDE FOR EARLY AND/OR LATE €ˌOMICS-FOCUSED NECROPSY ANALYSIS OF A TO-BE-NAMED-LATER €œEFFECTIVE€Ͽ½ NON-RHCMV VACCINE. SINCE… |
| 2023-03-31 | Oregon Health & Science University | $5.06M | THE OVERALL GOAL OF THE OREGON HEALTH & SCIENCE UNIVERSITY (OHSU) PROGRAM IS TO INFORM THE RATIONAL DESIGN OF AN EFFECTIVE TB VACCINE BY IDENTIFICATION OF IMMUNE RESPONSES THAT ARE CAPABLE OF CONTROLLING OR ERADICATING… |
| 2023-03-31 | Stellenbosch University | $1.45M | THE WALZL LABORATORY AT STELLENBOSCH UNIVERSITY (SU) WILL BE RESPONSIBLE FOR OVERSEEING THE CLINICAL AND IMMUNOLOGICAL WORK (INCLUDING ON SITE DATA MANAGEMENT) OF THE PROJECT. SU WILL PROVIDE INPUT ON THE DESIGN OF… |
| 2022-10-31 | Oregon Health & Science University | $1.15M | THE OVERALL GOAL OF OUR PROGRAM IS TO INFORM THE RATIONAL DESIGN OF AN EFFECTIVE TB VACCINE BY IDENTIFICATION OF IMMUNE RESPONSES THAT ARE CAPABLE OF CONTROLLING OR ERADICATING MTB. WE WILL ACHIEVE THIS GOAL BY… |
| 2025-09-02 | Africa Health Research Institute | $936.1K | AFRICA HEALTH RESEARCH INSTITUTE (AHRI) WILL CONDUCT GLOBAL MOLECULAR MEASUREMENTS ON TB CASES AND CONTROLS IN THE VUKUZAZI COHORT TO DEFINE CORRELATES OF PROTECTION AND TEST HYPOTHESIZED MECHANISMS OF PROTECTION… |
| 2024-02-29 | University of Washington | $787.7K | THE OVERALL GOAL OF THE IMPAC-TB PROGRAM IS TO INFORM THE RATIONAL DESIGN OF AN EFFECTIVE TB VACCINE BY IDENTIFICATION OF IMMUNE RESPONSES THAT ARE CAPABLE OF CONTROLLING AND POTENTIALLY EVEN ERADICATING MTB. THE GALE… |
| 2023-03-31 | University of Washington | $780.8K | THE OVERALL GOAL OF THE IMPAC-TB PROGRAM IS TO INFORM THE RATIONAL DESIGN OF AN EFFECTIVE TB VACCINE BY IDENTIFICATION OF IMMUNE RESPONSES THAT ARE CAPABLE OF CONTROLLING AND POTENTIALLY EVEN ERADICATING MTB. THE GALE… |
| 2022-12-31 | Stellenbosch University | $775.7K | DR. WALZL WILL SERVE AS THE PI OF THE SUBCONTRACT TO SU AND WILL BE RESPONSIBLE FOR OVERSEEING THE CLINICAL AND IMMUNOLOGICAL WORK (INCLUDING ON SITE DATA MANAGEMENT) OF THE PROJECT. HE WILL ALSO COORDINATE SAMPLE… |
| 2023-12-31 | Oregon Health & Science University | $703.6K | THE OVERALL GOAL OF THE OREGON HEALTH & SCIENCE UNIVERSITY (OHSU) PROGRAM IS TO INFORM THE RATIONAL DESIGN OF AN EFFECTIVE TB VACCINE BY IDENTIFICATION OF IMMUNE RESPONSES THAT ARE CAPABLE OF CONTROLLING OR ERADICATING… |
| 2025-01-20 | Stellenbosch University | $603.9K | THE DU PLESSIS/WALZL LABORATORY AT STELLENBOSCH UNIVERSITY (SU) WILL BE RESPONSIBLE FOR THE CLINICAL AND IMMUNOLOGICAL WORK (INCLUDING ON-SITE DATA MANAGEMENT) OF THE PROJECT. SU WILL COORDINATE THE STUDY DESIGN,… |
| 2025-10-17 | Regents of the University of Minnesota | $601.1K | THE OVERALL GOAL OF THE IMPAC-TB PROGRAM IS TO INFORM THE RATIONAL DESIGN OF AN EFFECTIVE TB VACCINE BY IDENTIFICATION OF IMMUNE RESPONSES THAT ARE CAPABLE OF CONTROLLING AND POTENTIALLY EVEN ERADICATING MTB. WE WILL… |
| 2023-12-31 | Stellenbosch University | $570.0K | THE WALZL LABORATORY AT STELLENBOSCH UNIVERSITY (SU) WILL BE RESPONSIBLE FOR THE CLINICAL AND IMMUNOLOGICAL WORK (INCLUDING ON SITE DATA MANAGEMENT) OF THE PROJECT. SU WILL COORDINATE SAMPLE SHARING FROM EXISTING… |
| 2023-03-31 | Stellenbosch University | $525.7K | THE WALZL LABORATORY AT STELLENBOSCH UNIVERSITY (SU) WILL BE RESPONSIBLE FOR THE CLINICAL AND IMMUNOLOGICAL WORK (INCLUDING ON SITE DATA MANAGEMENT) OF THE PROJECT. SU WILL COORDINATE SAMPLE SHARING FROM EXISTING… |
| 2023-12-31 | London School of Hygiene and Tropical Medicine | $499.9K | THE SCOPE OF THIS SUBAWARD IS TO ISOLATE CELLS FROM THE TISSUES OF DECEASED PATIENTS AND THEN EXAMINE CELL SUBSET AND FUNCTION WITHIN THE TISSUES OF ACTIVE TB, LATENT TB AND UNINFECTED INDIVIDUALS. SPECIFICALLY IN THIS… |
| 2025-11-19 | Stellenbosch University | $422.0K | STATEMENT OF WORK – YEAR 7 (BASE)
THE DU PLESSIS/WALZL LABORATORY AT STELLENBOSCH UNIVERSITY (SU) WILL BE RESPONSIBLE FOR THE CLINICAL AND IMMUNOLOGICAL WORK (INCLUDING ON-SITE DATA MANAGEMENT) OF THE PROJECT. SU WILL… |
| 2025-10-16 | University of Washington | $415.0K | THIS STATEMENT OF WORK (SOW) OUTLINES THE ACTIVITIES THAT UNIVERSITY OF WASHINGTON (UW GERNER) WILL BE PERFORMING. NOTE THAT THE TASK NUMBERS BELOW REFLECT THE NUMBERING OF THE OVERALL ACTIVITIES IN THE PRIME CONTRACT.… |
| 2023-12-31 | University of Washington | $410.8K | THE GERNER LABORATORY AT THE UNIVERSITY OF WASHINGTON (UW) SCHOOL OF MEDICINE DEPARTMENT OF IMMUNOLOGY HAS A MAJOR ROLE IN THE IMPAC-TB MICROSCOPY, HIGH-DIMENSIONAL FLOW CYTOMETRY AND SINGLE CELL RNA SEQUENCING… |
| 2025-12-18 | Oregon Health & Science University | $410.1K | STATEMENT OF WORK – YEAR 7 (BASE)
THE OVERALL GOAL OF THE OREGON HEALTH & SCIENCE UNIVERSITY (OHSU) PROGRAM IS TO INFORM THE RATIONAL DESIGN OF AN EFFECTIVE TB VACCINE BY IDENTIFICATION OF IMMUNE RESPONSES THAT ARE… |
| 2023-03-31 | University of Washington | $407.5K | THE GERNER LABORATORY AT THE UNIVERSITY OF WASHINGTON (UW) SCHOOL OF MEDICINE DEPARTMENT OF IMMUNOLOGY HAS A MAJOR ROLE IN THE IMPAC-TB MICROSCOPY, HIGH-DIMENSIONAL FLOW CYTOMETRY AND SINGLE CELL RNA SEQUENCING… |
| 2025-11-18 | Regents of the University of Minnesota | $394.9K | STATEMENT OF WORK – YEAR 7 (BASE) – GALE
THE GALE LABORATORY WILL PERFORM RNA-SEQ ASSAYS FOR THE NHP IMMUNOLOGIC STUDIES IN YEAR 7. WHOLE BLOOD AND TISSUE SAMPLES WILL BE RECEIVED AT THE GALE LABORATORY AT THE… |
| 2025-10-17 | Oregon Health & Science University | $383.5K | THE OVERALL GOAL OF THE OREGON HEALTH & SCIENCE UNIVERSITY (OHSU) PROGRAM IS TO INFORM THE RATIONAL DESIGN OF AN EFFECTIVE TB VACCINE BY IDENTIFICATION OF IMMUNE RESPONSES THAT ARE CAPABLE OF CONTROLLING OR ERADICATING… |
| 2023-03-31 | Beth Israel Deaconess Medical Center, Inc. | $370.4K | THE BAROUCH LABORATORY AT BETH ISRAEL DEACONESS MEDICAL CENTER (BIDMC) WILL WORK CLOSELY WITH THE URDAHL LABORATORY AT SEATTLE CHILDREN€„¢S RESEARCH INSTITUTE (SCRI) IN THE EVALUATION OF TB VACCINE CANDIDATES AND… |
| 2024-01-31 | Beth Israel Deaconess Medical Center, Inc. | $366.0K | RESEARCH EFFORTS DURING YEARS 1 THROUGH 4 RESULTED IN MAJOR FINDINGS INCLUDING SIGNIFICANT VACCINE PROTECTION WITH THE ΀?LPRG STRAIN IN THE LOW-DOSE MURINE AEROSOL CHALLENGE MODEL AND DEVELOPMENT OF A NOVEL… |
| 2025-10-16 | Beth Israel Deaconess Medical Center, Inc. | $363.8K | THIS STATEMENT OF WORK (SOW) OUTLINES THE ACTIVITIES THAT UNIVERSITY OF BETH ISRAEL DEACONESS MEDICAL CENTER (BIDMC) WILL BE PERFORMING. NOTE THAT THE TASK NUMBERS BELOW REFLECT THE NUMBERING OF THE OVERALL ACTIVITIES… |