Small Business Innovation Research · Small Business Technology Transfer
Physical Sciences Inc.: SBIR & STTR awards
193 awards worth $87.07M to 1 companies since 1985 match these filters. Phase I tests an idea (usually a few hundred thousand dollars); Phase II builds it (often $1M or more).
Physical Sciences Inc.'s federal contracts and grants · All SBIR & STTR awards
Awards by year
| Year | Phase I | Phase II | Amount |
|---|---|---|---|
| 2025 | 1 | 0 | $314.1K |
| 2024 | 3 | 0 | $897.5K |
| 2023 | 2 | 0 | $617.3K |
| 2022 | 2 | 6 | $11.77M |
| 2021 | 5 | 2 | $4.46M |
| 2020 | 5 | 2 | $3.77M |
| 2019 | 7 | 3 | $5.71M |
| 2018 | 5 | 5 | $6.88M |
| 2017 | 5 | 2 | $3.29M |
| 2016 | 2 | 1 | $1.95M |
| 2015 | 2 | 4 | $4.15M |
| 2014 | 11 | 2 | $4.49M |
The latest year fills in over months: agencies report awards to SBIR.gov with a lag.
Latest matching awards
| Award | Company | Agency | Phase | Amount | Date |
|---|---|---|---|---|---|
| Fast multicolor confocal fluorescence imager for neural network mapping · topic 101 | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $314.1K | 2025-01-01 |
| Virtual chromatographic cytometry for in-line biomanufacturing process analysis · topic 400 | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $302.4K | 2024-09-01 |
| High-Sensitivity Benzene Detector for Environmental Field Surveys · topic R | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $294.3K | 2024-06-04 |
| Head-mounted, high-speed confocal imager for voltage-sensitive neuronal recording · topic 101 | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $300.8K | 2024-02-05 |
| Evaluation of photoreceptors health and function in diabetic retinopathy patients using a high-resolution retinal imaging device with controlled light stimulus · topic 100 | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $331.1K | 2023-09-01 |
| Metabolic cytometry for in-line process analysis · topic 400 | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $286.2K | 2023-03-15 |
| Ultra-high speed AO-OCT clinical system to image ganglion cells and microglia · topic 100 | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $1.72M | 2022-09-30 |
| Smart sensor for guiding safe delivery of anesthetic and pain drugs through epidurals · topic NIGMS | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $294.4K | 2022-09-01 |
| Sensitive and spatially-selective quantification of oxygen in the headspace of pharmaceutical vials · topic 400 | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $263.0K | 2022-09-01 |
| Optical Redox Probe for Continuous Metabolic Monitoring during Natural Products Bioprocessing · topic NCCIH | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $1.77M | 2022-08-20 |
| Intelligent Optical Probe for Guiding Core Needle Biopsy Procedures · topic 102 | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $1.78M | 2022-05-23 |
| Advanced Intraoperative Imager for Nerve Identification · topic NIDCR | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $1.76M | 2022-04-01 |
| Supplemental support for the development of high spatiotemporal resolution neuronal imager · topic 101 | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $2.16M | 2022-03-14 |
| Ultra-Sensitive Vapor Phase Hydrogen Peroxide Sensor for Decontaminating Pharmaceutical Manufacturing Facilities · topic 400 | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $2.02M | 2022-02-01 |
| Smart Multi-grid Template for Focal Therapy of Prostate Cancer · topic NIBIB | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $263.0K | 2021-09-23 |
| Multi-modal cloud based system for detecting early signs of driver cognitive decline and/or high risk driving behaviors · topic NIA | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | STTR Phase I | $416.4K | 2021-08-15 |
| Multispectral cellular-level retinal imaging for early detection of Alzheimer’s disease · topic NIA | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $263.1K | 2021-08-01 |
| Ultra-sensitive Singlet Oxygen Dosimeter for Skin Cancer Treatment and Prevention · topic 102 | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $1.83M | 2021-07-01 |
| Electrohydraulic impactor for peripheral arterial occlusion management · topic NHLBI | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $263.1K | 2021-04-01 |
| Comprehensive imaging and quantification of blood flow for investigating ocular diseases without additional contrast agent · topic 100 | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $1.16M | 2021-03-01 |
| Versatile Eye Tracking for Improved High-resolution Retinal Imaging · topic NEI | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $258.4K | 2021-01-01 |
| Quantitative Methane Plume Imager for Localization and Flow Rate Estimation in Mines · topic NIOSH | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · Centers for Disease Control and Prevention | SBIR Phase II | $1000.0K | 2020-09-01 |
| Endoscopic Multifunctional Optical Coherence Tomography for Airway Tissue Injury Management · topic NHLBI | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $258.6K | 2020-09-01 |
| Multimodal Optical Probe for Skin Cancer Detection and Therapy Guidance · topic 399 | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $1.41M | 2020-07-27 |
| Ultra-sensitive Singlet Oxygen Dosimeter for Skin Cancer Treatment and Prevention · topic 102 | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $400.0K | 2020-05-06 |
| Ultra-Sensitive Vapor Phase Hydrogen Peroxide Sensor for Decontaminating Pharmaceutical Manufacturing Facilities and Equipment · topic 400 | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $231.3K | 2020-02-01 |
| Optical probe for in situ assessment of pulmonary fibrosis · topic NHLBI | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $230.0K | 2020-02-01 |
| Optical Redox Probe for Continuous Metabolic Monitoring during Natural Products Bioprocessing · topic NCCIH | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $232.3K | 2019-12-20 |
| Advanced Intraoperative Fluorescence Imager for Nerve Identification · topic NIDCR | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $229.9K | 2019-09-16 |
| Multi-channel functional imaging tool for neuropsychological drug development · topic 101 | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $446.1K | 2019-09-05 |
| Smart template for prostate biopsy guidance · topic 102 | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $1.18M | 2019-09-01 |
| Oximetry of Retinal Microvasculature in Rodent Eyes with Multi-modal Adaptive Optics Small-animal Imager · topic NEI | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $239.1K | 2019-09-01 |
| Comprehensive imaging and quantification of blood flow for investigating ocular diseases without additional contrast agent · topic NEI | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $230.0K | 2019-09-01 |
| Multimodal Optical Probe for Skin Cancer Detection and Therapy Guidance · topic 399 | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $300.0K | 2019-07-18 |
| Quality by Design Process Development Tools for Freeze Drying Co-solvent Pharmaceutical Formulations · topic 102 | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $224.0K | 2019-07-01 |
| Multimodal Endoscopic Probe for Inner Ear Hearing Loss Diagnosis and Therapy Guidance · topic NIDCD | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $1.06M | 2019-05-06 |
| SBIR PHASE II: LABHAND PAYLOAD FOR INSTANTEYE SUAS PLATFORM FOR CONTINUOUS AUTONOMOUS INDOOR TRANSPORT OF LABORATORY CONSUMABLES · topic NIDA | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $1.50M | 2019 |
| TOPIC 383: PERCUTANEOUS BIOPSY SYSTEM USING A SMART MULTICORE NEEDLE (MOONSHOT) · topic NCI | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $299.9K | 2019 |
| Quantitative Methane Plume Imager for Localization and Flow Rate Estimation in Mines · topic NIOSH | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · Centers for Disease Control and Prevention | SBIR Phase I | $150.0K | 2019-08-01 |
| Multi-modal AO-LSO Phase Gradient Imaging of the Inner Retina · topic NEI | Physical Sciences Inc. · Massachusetts | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $1.04M | 2018-09-30 |
Source: SBIR.gov award data (SBA) ↗, awards through 2026-08-28. Amounts are as agencies report them to SBA. SBIR/STTR contracts also appear in USAspending as ordinary awards; grants (NIH, NSF, DOE) appear as assistance. Open topics are posted by each agency; see Opportunities for contract notices.