Small Business Innovation Research · Small Business Technology Transfer
Epicypher, Inc.: SBIR & STTR awards
64 awards worth $79.15M to 1 companies since 2014 match these filters. Phase I tests an idea (usually a few hundred thousand dollars); Phase II builds it (often $1M or more).
Epicypher, Inc.'s federal contracts and grants · All SBIR & STTR awards
Awards by year
| Year | Phase I | Phase II | Amount |
|---|---|---|---|
| 2025 | 0 | 3 | $3.56M |
| 2024 | 0 | 4 | $9.68M |
| 2023 | 2 | 5 | $14.30M |
| 2022 | 4 | 5 | $12.93M |
| 2021 | 2 | 4 | $9.78M |
| 2020 | 1 | 4 | $8.93M |
| 2019 | 5 | 1 | $3.41M |
| 2018 | 6 | 4 | $9.35M |
| 2017 | 3 | 2 | $3.75M |
| 2016 | 5 | 1 | $2.76M |
| 2015 | 2 | 0 | $470.6K |
| 2014 | 1 | 0 | $220.2K |
The latest year fills in over months: agencies report awards to SBIR.gov with a lag.
Latest matching awards
| Award | Company | Agency | Phase | Amount | Date |
|---|---|---|---|---|---|
| Development of novel epigenetic biomarkers and detection reagents for aging · topic NIA | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $1.25M | 2025-09-20 |
| Asymmetric nucleosome substrates to advance the study of the histone code · topic 400 | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $1.26M | 2025-09-01 |
| Epigenomic analysis of cell-free nucleosomes for cancer research · topic 102 | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $1.05M | 2025-08-01 |
| Versatile platform for genome-wide R-loop mapping for aging and neurodegenerative disease research · topic NIA | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $2.55M | 2024-09-25 |
| Scalable and quantitative chromatin profiling from formalin-fixed paraffin-embedded samples · topic 172 | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $2.04M | 2024-09-10 |
| Versatile genomics platform for unbiased analysis of chromatin-associated RNAs and nascent transcripts · topic NIA | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $2.54M | 2024-08-15 |
| Biochemical and genomic tools to study histone ADP ribosylation signaling · topic 300 | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $2.55M | 2024-03-01 |
| Multiomic genomic mapping with long read sequencing · topic 400 | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $2.54M | 2023-09-01 |
| Rapid and robust assay for measurement of in vivo activity of chromatin-interacting proteins · topic NIAID | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $3.03M | 2023-07-19 |
| Epigenomic analysis of cell-free nucleosomes for cancer research · topic 102 | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $406.4K | 2023-07-01 |
| Novel recombinant sensors to study histone ubiquitin signaling · topic 400 | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $2.55M | 2023-06-01 |
| Scalable and quantitative chromatin profiling from formalin-fixed paraffin-embedded samples · topic 172 | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $406.3K | 2023-05-01 |
| Development of ultra-efficient antibodies for single cell mapping applications · topic NIAID | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $3.02M | 2023-03-10 |
| Ultrasensitive multiomic platform using epitope-targeted DNA methylation mapping · topic 172 | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $2.35M | 2023-02-01 |
| A novel platform for quantification of acute neuronal transcriptional responses · topic NIDA | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $326.5K | 2022-09-15 |
| Development of a high-throughput epigenomic mapping platform to molecularly phenotype Crohn's disease · topic 300 | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $1.98M | 2022-09-01 |
| High-resolution genomic mapping of ssDNA and associated proteins for Alzheimer's disease research · topic NIA | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $500.0K | 2022-09-01 |
| Multiomic genomic mapping with long read sequencing · topic 400 | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $406.4K | 2022-09-01 |
| Quantitative mapping of dynamic epigenetic states in rare and stimulated immune cells · topic NIAID | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $3.04M | 2022-08-18 |
| Quantification of combinatorial epigenetic modifications using defined nucleosome standards · topic 400 | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $2.05M | 2022-06-01 |
| A molecular toolbox to accelerate drug development for histone lysine methylation regulators · topic 100 | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $2.05M | 2022-05-01 |
| Ultrasensitive multiomic platform using epitope-targeted DNA methylation mapping · topic NHGRI | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $529.8K | 2022-02-01 |
| Engineered super-affinity reagents for detection of histone post-translational modifications · topic 400 | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $2.05M | 2022-01-20 |
| Development of a high-throughput epigenomic mapping platform to molecularly phenotype Crohn's disease · topic 300 | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $301.9K | 2021-09-15 |
| Quantitative mapping of combinatorial histone modifications · topic 172 | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $2.05M | 2021-09-09 |
| Development of efficient quantitative chromatin profiling in kit and high-throughput formats · topic 172 | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $2.05M | 2021-09-01 |
| Development of ultra-efficient antibodies for single cell mapping applications · topic NIAID | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $306.5K | 2021-07-01 |
| A new epigenetic toolbox for inflammation research and drug discovery · topic NIAID | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $3.04M | 2021-05-05 |
| Single-Cell Chromatin Mapping Assays · topic 400 | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $2.04M | 2021-04-06 |
| Development of novel spike-in controls for quantitative chromatin-associated protein profiling · topic NIDCR | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $1.96M | 2020-09-13 |
| Development of efficient quantitative chromatin profiling in kit and high-throughput formats · topic NHGRI | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $396.8K | 2020-09-01 |
| Rapid quantification of nuclear citrullination in human neutrophils · topic NIAID | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $2.95M | 2020-02-25 |
| Multiplex nucleosome-based profiling for the development of next-generation chromatin labeling reagents · topic 400 | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $1.84M | 2020-02-03 |
| Quantitative and highly versatile chromatin accessibility platform · topic 172 | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $1.79M | 2019-12-05 |
| Development of novel spike-in controls for quantitative chromatin-associated protein profiling · topic NIDCR | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $259.1K | 2019-09-13 |
| Development of highly specific and renewable chromatin labelling reagents · topic 400 | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $300.1K | 2019-08-15 |
| Novel enzyme inhibitor screening platform using modified designer nucleosomes · topic 300 | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase II | $1.97M | 2019-08-05 |
| Quantitative mapping of combinatorial histone modifications · topic 172 | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $285.0K | 2019-06-12 |
| Quantitative assessment of response to epigenetic-targeted therapy · topic 102 | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $299.8K | 2019-06-01 |
| Quantification of combinatorial epigenetic modifications using defined nucleosome standards · topic 400 | Epicypher, Inc. · North Carolina | Department of Health and Human Services · National Institutes of Health | SBIR Phase I | $299.9K | 2019-01-01 |
Source: SBIR.gov award data (SBA) ↗, awards through 2026-08-28. Amounts are as agencies report them to SBA. SBIR/STTR contracts also appear in USAspending as ordinary awards; grants (NIH, NSF, DOE) appear as assistance. Open topics are posted by each agency; see Opportunities for contract notices.